Аннотация:This work considers the possibilities of the excitation and induced decay of nuclear isomers using the promising quasi-monochromatic inverse Compton source ICS which is under development at the National Center for Physics and Mathematics. Experimentally confirmed cases of photoinduced de-excitation of isomers, such as 180mTa, 108mAg, and 68mCu, are discussed, and the obtained quantitative estimates for future photonuclear experiments, in particular on the isotopes 165Ho and 199Hg, are presented. It is shown that the planned parameters of the inverse Compton source, such as beam intensity and monochromaticity, will enable future high-precision measurements with a high signal-to-noise ratio. The obtained estimates of the count rate and the number of registered γ-quanta using an HPGe detector confirm the feasibility of performing activation experiments, as well as demonstrate the potential of the developed facility for addressing a broad range of tasks in nuclear photonics, including studies of nuclear structure and isomer decay mechanisms.