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Bioresorbable ceramics based on the Mg3(PO4)2–Mg2P2O7 system for bone tissue regenerationстатья Исследовательская статья
Статья опубликована в высокорейтинговом журнале
Информация о цитировании статьи получена из
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 15 апреля 2026 г.
- Авторы: Rassolova Yu R., Murashko A.M., Filippov Ya Yu, Davydova G.A., Selezneva I.I., Evdokimov P.V., Klimashina E.S., Putlayev V.I.
- Журнал: Ceramics International
- Год издания: 2026
- Издательство: Pergamon Press Ltd.
- Местоположение издательства: United Kingdom
- DOI: 10.1016/j.ceramint.2026.02.214
- Аннотация: Magnesium phosphate powder precursors, specifically magnesium orthophosphate (Mg3(PO4)2), magnesium pyrophosphate (Mg2P2O7), and a eutectic composition based on them (3Mg3(PO4)2/2Mg2P2O7), were synthesized via aerosol pyrolysis and solid-phase synthesis. Post-pyrolysis annealing at 700 oC was employed to prevent cracking during ceramic processing. Sintering proved most effective for the eutectic composition, regardless of the synthesis method used Sintering ceramics at 1100 oC for 3 h, obtained from precursors after pyrolysis, made it possible to achieve a compressive strength of 170 ± 2 MPa. When the temperature was increased to 1200 oC, materials produced via the solid-phase method exhibited the highest compressive strength of 130 ± 6 MPa. The resulting ceramic materials maintained solution pH values between 7.4 and 8.5, a range suitable for clinical applications. Resorption studies in a citric acid model medium indicated that solubility increased with higher Mg:P ratios, suggesting that these biphasic ceramic materials are promising candidates for further in vivo studies. All synthesized samples demonstrated both biocompatibility and bioactivity.
- Добавил в систему: Рассолова Юлия Романовна
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