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Biomechanical properties of lenticules in the ReLEx® SMILE® minimally invasive surgery: Do the age and degree of myopia matter?статья
Информация о цитировании статьи получена из
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 4 марта 2026 г.
- Авторы: Kukanova V.S., Dzamikhova A.K., Akovantseva A.A., Frolova A.A., Efremov Yu M., Shilova T.Yu, Svistunov A.A., Avetisov S.E., Timashev P.S., Kotova S.L.
- Журнал: Clinical Biomechanics
- Том: 125
- Год издания: 2025
- Издательство: Pergamon Press Ltd.
- Местоположение издательства: United Kingdom
- Номер статьи: 106508
- DOI: 10.1016/j.clinbiomech.2025.106508
- Аннотация: Background: Myopia is currently the most common refractive disorder of the eye. The important role of the cornea’s biomechanical parameters in relation to myopia has long been acknowledged, and ReLEx® SMILE minimally invasive refractive surgery offers new possibilities in the corneal biomechanical studies. The reported data on the role of the age and myopia degree in the corneal biomechanics are inconsistent. Methods: We have examined a considerable number (122 in total) of SMILE-derived lenticules from patients of different ages and with different severity of myopia, using atomic force microscopy, microtester and tensile testing.Findings: The mechanical properties of lenticules varied in a wide range and differed for the different techniques used. No differences between the Young’s moduli of the anterior and posterior sides of lenticules were observed. The age-related stiffening of the cornea found in some studies was not registered in our study, with >150 samples of patients aged from 17 to 47 years. Significantly lower tensile moduli of lenticules from moderate and high myopic eyes were measured by tensile testing in high-strain conditions, while no correlation was found using other techniques. The structural atomic force microscopy imaging studies demonstrated a mostly chaotic 3D network of collagen fibrils, while the roughness was independent of the myopia severity.Interpretation: No fundamental effect of the age and myopia degree on the corneal mechanical properties and morphology has been shown. The inconsistency of findings reported in the literature are due to the high dispersion of experimental data and specifics of the measurement techniques.
- Добавил в систему: Ефремов Юрий Михайлович