Аннотация:In an attempt to enhance the therapeutic effect ofcraniospinal irradiation (CSI) through dose escalation, a retrospectivestudy investigated the use of radiotherapy in a hyperfractionated mode(HFRT). The aim of this study was to compare event-free survival (EFS)and overall survival (OS) in children and adolescents withmedulloblastoma who received radiotherapy in standard fractionationmode (STRT) versus hyperfractionation mode (HFRT).