Аннотация:Nowadays, magnetic biosensors are being actively developed to detect and count requiredanalytes in labs-on-a-chip – miniature devices that perform the functions of a diagnostic laboratory in vitro. Magnetic biosensors detect changes in the magnetic field created by magnetic nanoparticles (MNPs) conjugated to biomolecules or penetrated into cells. For that reason, universal technologies for synthesizing MNPs without chemical impurities, with a given size distribution and desired properties are required.Pulsed laser ablation in liquid (PLAL) is a promising single-stage technology to produceMNPs. The advantages of PLAL are the ability to synthesize chemically pure nanoparticles andcontrol their size and composition by varying laser parameters and choosing an appropriate buffer liquid.In our work, to fabricate MNP suspensions, we irradiated magnetron-sputtered Co nanofilmswith a thickness varying in the range from 5 to 500 nm in distilled water with picosecond laser pulses (1064 nm, 34 ps, 5 mJ, 10 Hz) for 60 minutes. The use of such targets in PLAL instead of bulk materials can add opportunities to control a size distribution, morphology and composition of laser-ablated MNPs.
