Аннотация:Convenient syntheses of functionalized 2-hydroxyalkyl-substituted organophosphorus acids and their derivatives based on nucleophilic addition of trimethylsilyl esters of tricoor-dinated phosphorus acids to functionalized oxiranes have been developed. 2-Trimethyl-siloxyalkyl-substituted phosphonites are ef ective synthons for the production of new functionalized 2-hydroxyalkyl-substituted organophosphorus acids bearing amino, carboxy or sulfo groups. The resulting compounds are of interest as potential bioactive substances, promising extractants and polydentate ligands.