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Environmental contamination with dioxins: experience of ecotoxicity survey and assessment using wild mammalian model (bank vole C. glareolus) inhabiting forests outside sanitary zones of municipal waste landfillsстатья Исследовательская статья
Информация о цитировании статьи получена из
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 15 октября 2025 г.
- Авторы: Umnova Nataliya V., Myshliavkina Tatiyana A., Lavrenov Anton R., Shelepchikov Andrey A., Roumak Vladimir S.
- Журнал: Environmental Science and Pollution Research
- Том: 32
- Год издания: 2025
- Издательство: Springer Nature
- Местоположение издательства: Switzerland
- Первая страница: 5911
- Последняя страница: 5923
- DOI: 10.1007/s11356-025-36050-x
- Аннотация: Dioxins are known to be toxic for biota at every dose and their long-term efects are reported for almost 50 years of investigations. Our researches of dioxin accumulation by bank voles living in the vicinity of several landflls near Moscow (landflls“Lesnaya” and “Kouchino”) demonstrated the similarity of dioxin profles in soil and animal samples, and an increase ofhighly toxic congeners’ concentrations in the bank voles’ bodies. We investigated also the probable public cancer risk resulting from the comparable lifetime exposure of the voles’ population with dioxins’ low doses, and our evaluation verifed thehazard of cancer development supported by alterations in the ahr gene expression in the liver cells. The results of this studydetermined the usefulness of calculating the probability of cancer development in hypothetical residents of the area aroundboth landflls. For the landfll “Lesnaya,” the values corresponded to the level acceptable for professional groups (3.72E04), but unacceptable for the population, whereas for residents of the area in the vicinity of the landfll “Kouchino,” thelevel was considered to be unacceptable (1.91E-03) neither for the population nor for the professional groups. The revealedecotoxicological situation may be quite hazardous for the population living in the area contaminated with dioxins, and thehuman health risks should be assessed. Thus, the prospects of the initial public health screening should consider our set oftechniques used, as the efects described permit taking into account the mechanisms of interaction between the environmentalfactors and those determined by the characteristics of population real exposure.
- Добавил в систему: Лавренов Антон Русланович