Аннотация:A model for metabolism of the last bacterial common ancestor based on biomimetic analysis of the metabolic systems of phylogenetically ancient bacteria is developed. The mechanism of natural selectionand evolution of the autocatalytic chemical systems under the effect of natural homeostatic parameters, such as chemical potentials, temperature, and pressure of environment is proposed. Competition between partic ular parts of the autocatalytic network with positiveplusnegative feedback resulted in the formation of particular systems of primary autotrophic, mixotrophic, and heterotrophic metabolism. The model of the last common ancestor as a combination of coupled metabolic cycles among population of protocells is discussed. Physicochemical features of these metabolic cycles determined the major principles of natural selection towards ancestral bacterial taxa.
