|
ИСТИНА |
Войти в систему Регистрация |
ИСТИНА ПсковГУ |
||
Comparison of the Behavior of Rats after Prolonged Immobilization with Structural Changes in the Motor Cortex and Hippocampusстатья
Информация о цитировании статьи получена из
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 26 декабря 2017 г.
- Авторы: Levshina I.P., Mats V.N., Pasikova N.V., Shuikin N.N.
- Журнал: Neuroscience and Behavioral Physiology
- Том: 41
- Номер: 6
- Год издания: 2011
- Издательство: Kluwer Academic/Plenum Publishers
- Местоположение издательства: United States
- Первая страница: 599
- Последняя страница: 605
- DOI: 10.1007/s11055-011-9461-2
- Аннотация: Behavioral and neuron-glial ratios in the motor neocortex and hippocampus after stress induced by discontinuous (7–8 h/day for three weeks) immobilization were compared in Wistar rats (n = 23). Immobilization led to suppression of motor and orientational activity in the open field test and increases in the numbers and durations of episodes of freezing. Morphometric measurements demonstrated significant increases in the density of neurons with hypoxic changes in hippocampal field CA3 and a three-fold increase in this value in the motor zone of the cortex in both hemispheres of experimental animals as compared with controls. No clear glial cell reaction was seen in the motor cortex. Increases in the density of glial elements and the number of multinucleolar neurons in field CA3 provide evidence of compensatory processes occurring in the brain. Hypoxic changes to neurons were functional in nature. KEY WORDS open field test behavior rats immobilization motor cortex hippocampus neurons glia
- Добавил в систему: Мац Валентина Николаевна
Прикрепленные файлы
| № | Имя | Описание | Имя файла | Размер | Добавлен |
|---|---|---|---|---|---|
| 1. | Полный текст | 2011_Comparison_of_the_Behavior_of_Rats_after_Prolonged.pdf | 112,7 КБ | 26 марта 2018 [matz_vn] |