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The Influence of Combined Sterilization Factors on the Structural and Functional Characteristics of Bone Implantsстатья
Статья опубликована в высокорейтинговом журнале
Информация о цитировании статьи получена из
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 15 февраля 2024 г.
- Авторы: Nikolaeva Nadezhda, Rozanov Vladimir, Chernyaev Alexander, Matveychuk Igor, Makarova Milena
- Журнал: International Journal of Molecular Sciences
- Том: 24
- Номер: 19
- Год издания: 2023
- Издательство: MDPI
- Местоположение издательства: Basel, Switzerland
- Первая страница: 1
- Последняя страница: 11
- Номер статьи: 14426
- DOI: 10.3390/ijms241914426
- Аннотация: The results of a comprehensive study of the patterns of structural and functional changesin bone tissue samples after combined (ozone + radiation) sterilization are presented. The study useda different approach to the sterilization process with selective ozone or radiation exposure and anintegral, combined one, based on a combined ozone–oxygen treatment of bone samples at the firststage and radiation at the second. The methods of IR spectroscopy, scanning electron microscopy witha prefix for elemental analysis, atomic force microscopy, and mechanical analysis with determinationof elastic-plastic properties (Vickers microhardness index) were used in the work. It is shown that theozone exposure used at the first stage of the combined sterilization process of bone implants doesnot lead to negative consequences with respect to their properties and characteristics. The resultsobtained serve as a scientific and methodological basis for the further improvement and optimizationof sterilization technologies (including combined). They also offer a comprehensive justification of theparameters of sterilization regimes to ensure the safety of using bone implants during reconstructiveoperations, minimizing structural and functional changes in bone matter, and creating effectivehealth-saving technologies and the possibility of using them for various biomedical applications.
- Добавил в систему: Розанов Владимир Викторович
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