Аннотация:Introduction/Purpose: Optic nerve sheath meningioma (ONSM) is a slowly growing tumour that ispredominantly benign and unilateral. Meningioma may affect the orbital or canalicular portion of theoptic nerve, and may grow intracranially. Clinically, they are associated with optic neuropathy, includingslowly progressive vision loss, visual field defect, afferent pupillary defect, and loss of colour vision. Eyefundus findings are presented by the triad of symptoms: optic nerve atrophy, swelling of the optic disc,and sometimes development of optociliary shunt vessels. Some patients have proptosis and limitations ofeye movement, depending on the size of the tumour. Surgical treatment of ONSM is not an option as itusually causes permanent blindness. Fractionated radiotherapy (FCRT) has been recommended forONSM. Our purpose was to assess the visual outcome after radiotherapy/radiosurgery for managementoptic nerve sheath meningiomas.Materials and Methods: Between 2004 and 2018, 112 patients with ONSMs underwent FCRT in ourcentre. Out of 112, 99 were females and 12 males, aged from 17 to 76 (median 48 years), and one childaged 8. Among 112 patients, 24 were treated by hypofractionated radiotherapy with CyberKnife, and 88underwent standard fractionated radiotherapy with Novalis. A total of 93 patients were followed up(range 6 months to 12 years; median 57 months). In 74 patients, visual acuity varied from light perceptionto normal. Nineteen patients had blindness of the affected eye.Results: Forty-two patients (45.1%) had visual improvement; and in 32 patients (34.4%), all visualfunctions remained stable. The improvement started during the therapy and went on for a period of12 months and longer. There were no dynamics of visual functions in blind eyes. There was no visualdeterioration during the follow-up period.Discussion: Our experience has demonstrated that radiotherapy is a safe and effective long-termtherapeutic option in the management of ONSM. Also, it has proved to be effective in tumour controland stabilising or even restoring vision function.
