|
ИСТИНА |
Войти в систему Регистрация |
ИСТИНА ПсковГУ |
||
Effectiveness of an add-on treatment with the homeopathic medication SilAtro-5-90 in recurrent tonsillitis: An international, pragmatic, randomized, controlled clinical trialстатья
- Авторы: Palm Jürgen, Kishchuk Vasyl V., Ulied Àngels, Fernández Joaquin Perotti, Jaegere Sabine De, Jong Miek C., Keller Thomas, Kosakovskyi Anatolii, Kompaniiets Kira, Mityuryayeva-Korniiko Inga, Pukhlik Sergiy M., Tretiakevych Zoia, Weber Stephan, Wienhold Karin, Klement Petra
- Журнал: Complementary Therapies in Clinical Practice
- Том: 28
- Год издания: 2017
- Издательство: Elsevier BV
- Местоположение издательства: Netherlands
- Первая страница: 181
- Последняя страница: 191
- DOI: 10.1016/j.ctcp.2017.05.005
- Аннотация: Objective: To investigate the effectiveness and safety of the homeopathic product SilAtro-5-90 in recurrent tonsillitis.Methods: In this international, pragmatic, controlled clinical trial, 256 patients (6-60 years) with moderate recurrent tonsillitis were randomized to receive either SilAtro-5-90 in addition to standard symptomatic treatment, or to receive standard treatment only. The primary outcome was the mean time period between consecutive acute throat infections (ATI) within 1 year (analyzed via repeated events analysis).Results: During the evaluation year, the risk of getting an ATI was significantly lower (hazard ratio: 0.45, proportional means model, p = 0.0002, ITT) with SilAtro-5-90 compared to control. Tonsillitis-specific symptoms were significantly reduced (p < 0.0001, ITT) and the need of antibiotics to treat acute throat infections (p = 0.0008; ITT) decreased. 3 non-serious adverse drug reactions were reported for SilAtro-5-90.Conclusions: An integrative treatment approach where SilAtro-5-90 is given alongside mainstream symptomatic treatment may bring therapeutic benefit to patients suffering from recurrent tonsillitis.Trial registration: ISRCTN registry: Registration number ISRCTN19016626, registered 23 January 2013.Keywords: Acute throat infection; Homeopathy; Randomized controlled trial; Recurrent tonsillitis; SilAtro-5-90; Tonsilotren.
- Добавил в систему: Иванова Наталья Владимировна