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Repeated experience of social defeats increases serotonin transporter and monoamine oxidase A mRNA levels in raphe nuclei of male miceстатья
Информация о цитировании статьи получена из
Web of Science,
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 27 октября 2021 г.
- Авторы: Filipenko M.L., Beilina A.G., Alekseyenko O.V., Dolgov V.V., Kudryavtseva N.N.
- Журнал: Neuroscience Letters
- Том: 321
- Номер: 1-2
- Год издания: 2002
- Издательство: Elsevier BV
- Местоположение издательства: Netherlands
- Первая страница: 25
- Последняя страница: 28
- DOI: 10.1016/s0304-3940(01)02495-8
- Аннотация: Serotonin transporter (SERT) and monoamine oxidase A (MAOA) mRNA levels in the raphe nuclei area of the midbrain were measured by the multiplex reverse transcription-polymerase chain reaction method in male mice with repeated experience of social victories (winners) and defeats (losers) in ten daily agonistic confrontations. Experiments revealed enhanced SERT and MAOA mRNA levels in the losers compared with the winners and controls. It has been supposed that SERT and MAOA genes are involved in enhancement of serotonin inactivation in response to the increase of serotonergic activity shown earlier in the losers. A positive correlation between MAOA and SERT mRNA levels in the raphe nuclei area of the midbrain was shown.
- Добавил в систему: Галямина Анна Георгиевна