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Smartphone-assisted electrochemical sensor for reliable detection of tyrosine in serumстатья
Статья опубликована в высокорейтинговом журнале
Информация о цитировании статьи получена из
Web of Science,
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 22 декабря 2021 г.
- Авторы: Luca Fiore, De Lellis Benedetta, Mazzaracchio Vincenzo, Suprun Elena, Massaoud Renato, Goffredo Bianca Maria, Moscone Danila, Arduini Fabiana
- Журнал: Talanta
- Том: 237
- Год издания: 2022
- Издательство: Elsevier BV
- Местоположение издательства: Netherlands
- Номер статьи: 122869
- DOI: 10.1016/j.talanta.2021.122869
- Аннотация: Point-of-care devices have attracted a huge interest by the scientific community because of the valuable potentiality for rapid diagnosis and precision medicine through cost-effective and easy-to-use devices for on-site measurement by unskilled personnel. Herein, we reported a smartphone-assisted electrochemical device consisted of a screen-printed electrode modified with carbon black nanomaterial and a commercially available smartphone potentiostat i.e. EmStat3 Blue, for sensitive detection of tyrosine. Once optimized the conditions, tyrosine was detected in standard solutions by square wave voltammetry, achieving a linear range comprised between 30 and 500 μM, with a detection limit equal to 4.4 μM. To detect tyrosine in serum, the interference of another amino acid i.e. tryptophan was hindered using a sample treatment with an extraction cartridge. The agreement of results analyzing serum samples with HPLC reference method and with the developed smart sensing system demonstrated the suitability of this smartphone-assisted sensing tool for cost-effective and rapid analyses of tyrosine in serum samples.
- Добавил в систему: Супрун Елена Владимировна
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