Инсерционно-делеционный полиморфизм гена ангиотензинпревращающего фермента у лиц с семейной артериальной гипертензией коренного населения Республики Мордовиястатья
Статья опубликована в журнале из списка RSCI Web of Science
Номер статьи:УДК 575. 113.1:616.12-008.331.1(470.345)(=511.152)
Аннотация:The study was aimed at examining the role of insertion-deletion polymorphism of angiotensin-converting enzyme gene in hypertension disease development in patients with familial arterial hypertension. 171 native inhabitants of the Republic of Mordovia, of both Mordovian and Russian nationalities were examined. The study performed by a polymerase chain reaction technigue has not shown confident distinctions in the occurrence of alleles and genotypes of I/D polymorphism in ACE gene among Mordovian and Russian patients with familial AH. No interrelation between D allel of ACE gene and AH disease development or AP level has been found.