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Involvement of protein kinase Mζ in the maintenance of long-term memory for taste aversion learning in young chicksстатья
Информация о цитировании статьи получена из
Web of Science,
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 6 декабря 2018 г.
- Авторы: Tiunova AA, Bezryadnov DV, Anokhin KV
- Журнал: Bulletin of Experimental Biology and Medicine
- Год издания: 2015
- Издательство: Springer Nature
- Местоположение издательства: Switzerland
- Первая страница: 158
- Последняя страница: 5
- DOI: 10.1007/s10517-015-2813-0
- Аннотация: The effects of an inhibitor of protein kinase Mζ on long-term memory were studied using the model of taste aversion in newborn chicks. Memory was impaired by intracerebral injection of 10 or 20 nmol of ζ-inhibiting peptide 24 h after training. Memory impairment was found 2 h after peptide administration, and repeated examination 24 h after treatment showed no recovery. Memory impairment was not observed 24 h after inhibitor administration if the testing 2 h after treatment was not performed. The results indicate the contribution of protein kinase Mζ in the maintenance of long-term memory in the avian brain. These data confirm the hypothesis of several authors that inhibition of protein kinase Mζ does not abolish memory, but rather interacts with processes of memory retrieval and/or reconsolidation.
- Добавил в систему: Анохин Константин Владимирович