Аннотация:The paper dwells on the study of chirality of aqueous systems containing extrinsic chiral biological molecules of L-, D-valine and L-, D-glycerose and water clusters (H2O)4. Aqueous were obtained using the Avogadro software with the Conjugate Gradients algorithm. Using the Solvate software, molecules of L-, D-glycerose and L-, D-valine and water clusters (H2O)4 have been surrounded with the layer of H2O molecules of given thickness. The thickness varied from 4 Å to 14 Å with a step of 2 Å. The research indicated that for the aqueous system containing L-glycerose with 8Å thick aqueous layer the number of right-handed aqueous shells in the sample is greater than that of left-handed those. At that, for the system containing D-valine with 4Å thick aqueous layer the number of left-handed aqueous shells in the sample is greater than that of right-handed those.