ИСТИНА

Active development of technologies to create portable personal «lab-on-chip» devices for in vitro diagnostics is driven by the need to health monitoring and early diagnostics of diseases. A promising basis for such devices might be magnetic biosensors (MBS) that detect biomolecules conjugated with magnetic labels. To improve the detection limit of MBS, it is necessary to both improve fabrication technologies of magnetic labels and increase efficiency of their capture and retention on the sensor surface. In our work, we propose to apply laser nano- and microstructuring for this purpose in three directions: (i) fabrication of magnetic nanoparticles using pulsed laser ablation in liquids of thin cobalt and iron films; (ii) creating laser-induced periodic surface structures in a ferromagnet/antiferromagnet (F/AF) thin-film exchange biased multilayer based on NiFe/IrMn, which is an active element of a magnetoresistive sensor; (iii) local modulation of a micromagnetic structure of F/AF sample using heating with femtosecond laser pulses in the presence of an external magnetic field.