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The rapid growth of the chemical industry necessitates the development of innovative methods for assessing the safety and environmental efficiency of chemical processes. This paper presents a model for the comparative analysis of chemical processes based on the 12 principles of green chemistry. The model incorporates an informational block, a functional block, and a report output block to streamline assessment. A quantitative evaluation framework was developed using mathematical formulas and specific coefficients, which consider mass indicators and physicochemical parameters of processes producing the same chemical product. This approach enables a systematic comparison of environmental efficiency, contributing to the advancement of sustainable industrial practices.