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The analgesic effect of the 2H-chromene derivative CHR was investigated on a model of neuropathic pain induced by the ligation of the sciatic nerve in mice. From the 5th to the 7th day of the experiment, the analgesic effect of the CHR compound was not weaker than that of the comparison drug. Based on the computational data, we assume that the CHR compound is an allosteric modulator of the cannabinoid CB1 receptor.
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