ИСТИНА |
Войти в систему Регистрация |
|
ИСТИНА ПсковГУ |
||
A remarkable body of knowledge has been accumulated over the last decade on the molecular machinery responsible for antigen receptor signaling, on which initiation and execution of adaptive immunity to infection and cancer crucially relies. Thus equipped, we have been able to study lymphocyte development, activation and differentiation using sophisticated mouse models. With the development of new gene manipulation approaches, high throughput technologies and biophysical tools, we are now able to tackle the complexity of the human lymphocyte responses with high definition.